In our latest publication in Nature Communications, we show that peritoneal resident macrophages define a metastatic site-specific immunosuppressive niche, and that targeting these peritoneal resident macrophages is a promising treatment strategy for peritoneal...

A collaborative project with the group of Dr. Sarah Derks resulted in this publication in the Journal for ImmunoTherapy of Cancer. This paper shows that gastric cancer (GC)-derived peritoneal metastases often contain immature tertiary lymphoid structures (TLS), which...

A new paper from our group has been published in Frontiers in Immunology. The paper demonstrates that T cell responses in peritoneal metastasized colorectal cancer (PM-CRC) in a humanized immune system mouse model mirror those in human PM-CRC. This makes the model...

Joep Grootjans joins Oncode Institute per January 1st, 2024, together with 9 other Junior Investigators and their research groups. The Junior Investigators were selected out of 72 applicants based on the quality of their science, expertise and potential to contribute...

Four esteemed researchers within the Amsterdam Institute for Infection and Immunity (AII) have been granted VIDI awards by the prestigious Dutch Research Council (NWO). Dr. Sarah Derks is spearheading research in Cancer Immunology. She focuses on tackling...

https://www.youtube.com/watch?v=mzuXwchZnhM   TKI-PPP grant Amsterdam UMC stimulates its researchers to perform research projects together with companies in Public-Private Partnerships (PPP). The funding is provided by the Dutch government (Ministry of Economic...

Sofia Frigerio received the ECCO grant of 80k from the European Crohn’s and Colitis Organisation. With funding from the ECCO, she will study the role of the immune system in the development of dysplasia and cancer in humans using novel spatial profiling techniques.

New postdoc Hina Naz Khan: Hina Naz Khan has a bioinformatics background and will use innovative spatial profiling techniques and single-cell RNA-sequencing to study how the local tumor environment determines the tumor immune infiltrate in colorectal and gastric...